Serra Mesa Hotels, San Diego

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Check prices for these dates

Tonight
28 July - 29 July
Tomorrow
29 July - 30 July
This weekend
1 Aug - 3 Aug
Next weekend
8 Aug - 10 Aug

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8845 Cheap Hotels in Serra Mesa - Specials, Reviews, & Last Minute Deals

Sycuan Casino Resort
3 outdoor pools, pool cabanas (surcharge), pool umbrellas

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1430)
"We had a wonderful stay, will definitely visit again!"
Sycuan Casino Resort
Best Western Premier Hotel Del Mar
Front of property

Best Western Premier Hotel Del Mar

3.0 star property
9.2 out of 10, Wonderful, (1015)
"I love this hotel"
The price is AU$198
includes taxes & fees
3 Aug - 4 Aug
Best Western Premier Hotel Del Mar
La Quinta Inn by Wyndham San Diego Chula Vista
Exterior

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
8.6 out of 10, Excellent, (1321)
"Love the breakfast and convenient location. "
The price is AU$204
includes taxes & fees
29 July - 30 July
La Quinta Inn by Wyndham San Diego Chula Vista
Hotel Palmeras Chula Vista
Front of property

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1800)
"It’s was good experience staying in hotel "
The price is AU$133
includes taxes & fees
29 July - 30 July
Hotel Palmeras Chula Vista
Hercor Hotel - Urban Boutique
Deluxe Room, 1 King Bed

Hercor Hotel - Urban Boutique

3.0 star property
8.6 out of 10, Excellent, (1216)
"Great place to stay!"
The price is AU$177
includes taxes & fees
29 July - 30 July
Hercor Hotel - Urban Boutique
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Desk, blackout curtains, iron/ironing board, free WiFi

Studio 6 Suites San Ysidro, CA -San Diego South Bay

2.5 star property
7.8 out of 10, Good, (1156)
"Nice hotel to stay in "
The price is AU$139
includes taxes & fees
29 July - 30 July
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Sea Harbor Hotel
Marina

Sea Harbor Hotel

2.0 star property
8.6 out of 10, Excellent, (906)
"Great location, very customer friendly staff."
The price is AU$259
includes taxes & fees
29 July - 30 July
Sea Harbor Hotel
Valli Hi Motel
Desk, blackout curtains, soundproofing, free WiFi

Valli Hi Motel

2.5 star property
8.2 out of 10, Very good, (1030)
"Staff was friendly hotel was clean and easy day trips back and forth throughout San Diego area."
Valli Hi Motel
Bay Club Hotel & Marina
Exterior

Bay Club Hotel & Marina

3.5 star property
9.0 out of 10, Wonderful, (2768)
"Great place to stay"
The price is AU$248
includes taxes & fees
10 Aug - 11 Aug
Bay Club Hotel & Marina
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
Exterior

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

4.0 star property
9.2 out of 10, Wonderful, (431)
"The breakfast was great."
The price is AU$268
includes taxes & fees
3 Aug - 4 Aug
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
Legacy Resort Hotel & Spa
Garden

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2893)
"Great stay"
The price is AU$230
includes taxes & fees
24 Aug - 25 Aug
Legacy Resort Hotel & Spa
The Horton Grand, Downtown/Gaslamp Quarter
Serves dinner and happy hour

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.0 out of 10, Wonderful, (2432)
"Would stay there again when in town"
The Horton Grand, Downtown/Gaslamp Quarter
The Encinitan Hotel & Suites
Outdoor spa tub

The Encinitan Hotel & Suites

3.0 star property
8.0 out of 10, Very good, (1064)
"Great location / family friendly "
The Encinitan Hotel & Suites
Gaslamp Plaza Suites
Lobby

Gaslamp Plaza Suites

3.5 star property
8.8 out of 10, Excellent, (1019)
"I loved staying at this property! The hotel room was clean and the decor was beautiful. All dining was in walking distance as well."
The price is AU$189
includes taxes & fees
7 Aug - 8 Aug
Gaslamp Plaza Suites
La Quinta Inn & Suites by Wyndham San Diego Mission Bay
Free daily buffet breakfast

La Quinta Inn & Suites by Wyndham San Diego Mission Bay

3.0 star property
8.0 out of 10, Very good, (1333)
"Nestled in a great area close to pacific beach and I-5. "
The price is AU$189
includes taxes & fees
17 Aug - 18 Aug
La Quinta Inn & Suites by Wyndham San Diego Mission Bay
Humphreys Half Moon Inn
Outdoor pool

Humphreys Half Moon Inn

3.5 star property
9.2 out of 10, Wonderful, (2449)
"Great place to stay!!"
The price is AU$312
includes taxes & fees
18 Aug - 19 Aug
Humphreys Half Moon Inn
Best Western San Diego Pacific Beach/Mission Bay
Outdoor pool

Best Western San Diego Pacific Beach/Mission Bay

2.5 star property
7.2 out of 10, Good, (1260)
"Excellent hotel !! "
The price is AU$189
includes taxes & fees
3 Aug - 4 Aug
Best Western San Diego Pacific Beach/Mission Bay
Best Western Plus Marina Gateway Hotel
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed)

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3175)
"This location was great for our family get away"
The price is AU$255
includes taxes & fees
3 Aug - 4 Aug
Best Western Plus Marina Gateway Hotel
Pleasant Inn
1 bedroom, desk, laptop workspace, blackout curtains

Pleasant Inn

2.5 star property
8.4 out of 10, Very good, (1091)
"night staff awesome and welcoming, convenient to airport "
The price is AU$160
includes taxes & fees
11 Aug - 12 Aug
Pleasant Inn
Handlery Hotel
Outdoor pool, pool umbrellas, pool loungers

Handlery Hotel

3.5 star property
8.2 out of 10, Very good, (1920)
"The pool area is great and I loved the convenience of the restaurants. "
The price is AU$192
includes taxes & fees
10 Aug - 11 Aug
Handlery Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.
Downtown San Diego map

Downtown San Diego

2 out of top 10 points of interest in this area

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Belmont Park which includes a garden and rides
Mission Beach map

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach Park featuring a beach
Pacific Beach map

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Gaslamp Quarter featuring a bar, street scenes and a city
Gaslamp Quarter map

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Ocean Beach map

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Serra Mesa Hotel Reviews

Bay Club Hotel & Marina

Bay Club Hotel & Marina

10/10 Excellent
"Greater L"
Mauricio 1-night trip
Posted 2 days ago
Bay Club Hotel & Marina

Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

Where is the best place to stay in Serra Mesa?

For your stay in Serra Mesa, Cozy 2 bedroom unit with pool is one of the top choices based on our traveller data. Other good choices for your stay in the area include Centrally Located San Diego Condo w/Hot Tub & Pool and Central location - 3br/2ba. Stay weekly. Clean, safe, quiet. .

How many hotels can I expect to find in the Serra Mesa area?

Expedia has 36 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.

What can I see and do in this San Diego neighbourhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.