Serra Mesa Hotels, San Diego

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8788 Cheap Hotels in Serra Mesa - Specials, Reviews, & Last Minute Deals

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1468)
"The rooms are very clean and the restaurant options are good too."
Sycuan Casino Resort

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.6 out of 10, Good, (1001)
"Clean a quiet place"
The price is AU$157
includes taxes & fees
1 Sept - 2 Sept
Days Inn by Wyndham San Diego-East/El Cajon

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very good, (1003)
"Staff was friendly, hotel was clean and breakfast was great"
The price is AU$181
includes taxes & fees
1 Sept - 2 Sept
Best Western Plus La Mesa San Diego

Ramada by Wyndham San Diego Poway Miramar

2.0 star property
6.8 out of 10, (854)
"Our stay went well, and the hotel is a good value"
The price is AU$161
includes taxes & fees
7 Sept - 8 Sept
Ramada by Wyndham San Diego Poway Miramar

Sonesta ES Suites Carmel Mountain – San Diego

3.0 star property
8.4 out of 10, Very good, (916)
"I have stayed here many times. I like how clean it always is and the staff is very helpful. "
The price is AU$212
includes taxes & fees
28 Aug - 29 Aug
Sonesta ES Suites Carmel Mountain – San Diego

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1082)
"Prefect stay with the family. Would stay again and recommend to friends. "
Ayres Hotel San Diego South - Chula Vista

Heritage Inn La Mesa

2.0 star property
6.6 out of 10, (1051)
"Location, close 2 food & restaurants"
The price is AU$119
includes taxes & fees
10 Aug - 11 Aug
Heritage Inn La Mesa

La Quinta Inn by Wyndham San Diego - Miramar

3.0 star property
7.6 out of 10, Good, (1001)
"Nice stay"
The price is AU$157
includes taxes & fees
1 Sept - 2 Sept
La Quinta Inn by Wyndham San Diego - Miramar

Lamplighter Inn & Suites at SDSU

2.5 star property
9.0 out of 10, Wonderful, (1226)
"We will definitely be staying there again"
Lamplighter Inn & Suites at SDSU

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.8 out of 10, Good, (1461)
"Clean, great staff. "
The price is AU$200
includes taxes & fees
14 Aug - 15 Aug
Best Western Chula Vista/Otay Valley Hotel

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
8.6 out of 10, Excellent, (1336)
"Love the breakfast and convenient location. "
The price is AU$192
includes taxes & fees
1 Sept - 2 Sept
La Quinta Inn by Wyndham San Diego Chula Vista

Valli Hi Motel

2.5 star property
8.2 out of 10, Very good, (1001)
"Great hotel "
Valli Hi Motel

Chula Vista Inn

2.5 star property
6.6 out of 10, (1001)
"Pleasant quiet and so affordable. I look forward to coming back when their pool and Jacuzzi is fully functioning."
Chula Vista Inn

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1808)
"Nice spot short drive from DT San diego"
The price is AU$122
includes taxes & fees
10 Aug - 11 Aug
Hotel Palmeras Chula Vista

Hercor Hotel - Urban Boutique

3.0 star property
8.6 out of 10, Excellent, (1212)
"Great place to stay!"
The price is AU$160
includes taxes & fees
1 Sept - 2 Sept
Hercor Hotel - Urban Boutique

Howard Johnson by Wyndham National City/San Diego South

2.0 star property
7.4 out of 10, Good, (1001)
"Great place 👍"
The price is AU$137
includes taxes & fees
11 Aug - 12 Aug
Howard Johnson by Wyndham National City/San Diego South

SureStay Hotel by Best Western Chula Vista San Diego Bay

3.0 star property
7.8 out of 10, Good, (1466)
"Great place"
The price is AU$142
includes taxes & fees
13 Aug - 14 Aug
SureStay Hotel by Best Western Chula Vista San Diego Bay

Berkshire Motor Hotel

2.5 star property
8.4 out of 10, Very good, (956)
"Great location within walking distance from the places we wanted to visit."
The price is AU$164
includes taxes & fees
11 Aug - 12 Aug
Berkshire Motor Hotel

The Rambler Motel

3.0 star property
9.0 out of 10, Wonderful, (1875)
"This place is safe to stay and close to a lot of places to eat. "
The price is AU$194
includes taxes & fees
12 Aug - 13 Aug
The Rambler Motel

Sun Outdoors San Diego Bay

2.0 star property
10.0 out of 10, Exceptional, (71)
"A good place to stay with the whole family"
The price is AU$386
includes taxes & fees
27 Aug - 28 Aug
Sun Outdoors San Diego Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.
Downtown San Diego map

Downtown San Diego

2 out of top 10 points of interest in this area

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Mission Beach map

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach map

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Gaslamp Quarter map

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Ocean Beach map

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

Where is the best place to stay in Serra Mesa?

For your stay in Serra Mesa, Cozy 2 bedroom unit with pool is one of the top choices based on our traveller data. Other good choices for your stay in the area include Centrally Located San Diego Condo w/Hot Tub & Pool and Central location - 3br/2ba. Stay weekly. Clean, safe, quiet. .

How many hotels can I expect to find in the Serra Mesa area?

Expedia has 36 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.

What can I see and do in this San Diego neighbourhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.