Photo by Ryan Coleman

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Top hotels and accommodation in Sikeston

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1049)
"It was small room but was okay "
The price is AU$121
includes taxes & fees
7 Apr - 8 Apr
Pear Tree Inn Cape Girardeau Near the Medical Center

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1086)
"This was our first stay at a Drury Inn, and it won’t be our last. First of all we are responsible pet owners, and loved that we could find a nice hotel that would have them. Loved the social hour. Nice clean, quiet room, and friendly accommodating staff. A perfect stay for weary travelers."
The price is AU$170
includes taxes & fees
7 Apr - 8 Apr
Drury Plaza Hotel Cape Girardeau Conference Center

The Riverview

3.5 star property
9.2 out of 10, Wonderful, (196)
"Beautiful room, view, and great price. We will definitely be coming back! Thank you!"
The price is AU$158
includes taxes & fees
20 Apr - 21 Apr
The Riverview

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
9.0 out of 10, Wonderful, (519)
"Quiet, clean, cozy, reasonably priced!"
The price is AU$143
includes taxes & fees
6 Apr - 7 Apr
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1090)
"Our second visit in route back from New Orleans. Great location right off the highway. The hotel is clean, updated and staff are always friendly. Decent breakfast too. "
The price is AU$156
includes taxes & fees
6 Apr - 7 Apr
Pear Tree Inn Sikeston

Tru By Hilton Cape Girardeau

2.5 star property
10.0 out of 10, Exceptional, (2)
"New hotel. very nice."
The price is AU$183
includes taxes & fees
13 Apr - 14 Apr
Tru By Hilton Cape Girardeau

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1075)
"Nice place, would stay here again "
The price is AU$129
includes taxes & fees
7 Apr - 8 Apr
Pear Tree Inn Cape Girardeau West

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (910)
"Always like staying at Drury Inns. And the staff at this location especially the ones working the breakfast buffet are very welcoming and friendly! "
The price is AU$170
includes taxes & fees
27 Apr - 28 Apr
Drury Inn & Suites Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1058)
"We enjoyed our stay both times on our vacation to New Orleans."
The price is AU$185
includes taxes & fees
13 Apr - 14 Apr
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1037)
"Ive stayed here before and the quality only improves!"
The price is AU$151
includes taxes & fees
7 Apr - 8 Apr
Drury Inn & Suites Jackson MO

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (94)
"Very clean and updated"
The price is AU$167
includes taxes & fees
13 Apr - 14 Apr
Fairfield Inn & Suites by Marriott Cape Girardeau

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1076)
"We have stayed in many drury inn and suites in a variety of cities/towns and this was the best! Friendly people, great suite for a room, great breakfast. "
The price is AU$181
includes taxes & fees
6 Apr - 7 Apr
Drury Inn & Suites Sikeston, MO

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (404)
"Excellent property with excellent service!"
The price is AU$234
includes taxes & fees
27 Apr - 28 Apr
Courtyard by Marriott Cape Girardeau Downtown

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (696)
"It was clean and the beds were actually very comfortable. They never refilled the conditioner in the shower but that was the only complaint. "
The price is AU$197
includes taxes & fees
13 Apr - 14 Apr
Hampton Inn Cape Girardeau I 55 East

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very good, (1039)
"The gentleman at the front desk was super nice , friendly and just fun when we checked in , we had a quick overnight stay in town ! Pool was clean nice and warm , the next morning breakfast was nice clean and stocked and the young lady cleaning and keeping it full was very friendly also , plus we were able to have are Yorkie in room at a reasonable charge "
The price is AU$162
includes taxes & fees
6 Apr - 7 Apr
Best Western Plus Sikeston

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (325)
"Clean, friendly staff, breakfast had good choices, quiet. Great for family stay."
The price is AU$198
includes taxes & fees
13 Apr - 14 Apr
Hampton Inn Sikeston

Comfort Suites Jackson-Cape Girardeau

2.5 star property
8.2 out of 10, Very good, (692)
"V"
The price is AU$145
includes taxes & fees
3 Apr - 4 Apr
Comfort Suites Jackson-Cape Girardeau

Candlewood Suites Cape Girardeau by IHG

2.5 star property
8.2 out of 10, Very good, (747)
"Second time staying here for my family and I! We will stay again if in town. "
The price is AU$170
includes taxes & fees
20 Apr - 21 Apr
Candlewood Suites Cape Girardeau by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
8.6 out of 10, Excellent, (399)
"Clean "
The price is AU$221
includes taxes & fees
13 Apr - 14 Apr
Holiday Inn Express & Suites Sikeston Southwest by IHG

Days Inn and Suites by Wyndham Sikeston

2.0 star property
7.2 out of 10, Good, (1061)
"Everything was good for a guick one night stay. Nothing fancy but there were 5 of us and plenty of room. Breakfast not great but just enough choices for 3 adults and 2 kids. Only problem was pull out sofa bed was broken but it was big enough to just sleep on top. For the price it was good. I would recommend. "
The price is AU$139
includes taxes & fees
6 Apr - 7 Apr
Days Inn and Suites by Wyndham Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Where is the best place to stay in Sikeston?

Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Hampton Inn Sikeston. See all available top hotels, or vacation rentals in Sikeston.

What are some of the best holiday rentals that Sikeston has to offer?

Beautiful location in the secluded woods : This holiday home rental outside of Sikeston offers a fireplace, a patio and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. See all vacation rentals in Sikeston.

If I need to cancel my hotel reservation in Sikeston, will I receive a refund?

Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.

What's the best budget-friendly hotel in Sikeston?

Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. View all budget hotels in Sikeston.

What's the best family accommodation in Sikeston?

Pear Tree Inn Sikeston is a hotel with an outdoor pool and free breakfast, and it's a top choice on Expedia for families. Drury Inn & Suites Sikeston, MO is another good choice for your family trip. Also, children of all ages will enjoy a visit to The Book Bug. Find more child-friendly accommodations in Sikeston.

What's the best LGBTQ-friendly hotel in Sikeston?

Pear Tree Inn Sikeston is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Drury Inn & Suites Sikeston, MO and Hampton Inn Sikeston are two other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Sikeston.

What's the best dog-friendly hotel in Sikeston?

Pear Tree Inn Sikeston is a top hotel for people travelling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good choices for you and your pet's trip include Drury Inn & Suites Sikeston, MO and Days Inn and Suites by Wyndham Sikeston. See more pet-friendly hotel accommodations in Sikeston.

What's the best hotel for a golf holiday in Sikeston?

Travel Inn & Suites is a hotel featuring free breakfast and free WiFi, and it's a top choice for playing a round of golf. You can tee off at Boot Heel Golf Club during your trip. See more golf hotels in Sikeston.

What are some hotels with pools in Sikeston?

Best Western Plus Sikeston is a top hotel with a pool, free full breakfast and free self-parking. View all hotels with pools in Sikeston.

What is the best spa hotel in Sikeston?

Drury Inn & Suites Sikeston, MO is a top spa hotel featuring a pool and a fitness centre. See all spa hotels in Sikeston.

What is staying in Sikeston like?

Families will find child-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodation options to choose from. Find out more about Sikeston.

What is there to see in Sikeston?

Favourite places to visit include Sikeston Depot Museum, Boot Heel Golf Club and The Book Bug. Additionally, you might want to add Central Park to your itinerary. Take a look at what more there is to see and do in Expedia's Sikeston guide.

What's the seasonal weather in Sikeston?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Sikeston is 1536 mm.