Photo by Leonardo De Leon

Otay Mesa West Hotels, San Diego

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

6480 Cheap Hotels in Otay Mesa West - Specials, Reviews, & Last Minute Deals

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1110)
"Awesome thanks you"
The price is AU$187
includes taxes & fees
19 Feb - 20 Feb
Sycuan Casino Resort

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.8 out of 10, Good, (1003)
"Every was good except coffee maker started smoking."
The price is AU$156
includes taxes & fees
23 Feb - 24 Feb
Days Inn by Wyndham San Diego-East/El Cajon

Super 8 by Wyndham El Cajon/San Diego

2.0 star property
7.4 out of 10, Good, (1004)
"Best sleep ever. Very quiet"
The price is AU$155
includes taxes & fees
9 Feb - 10 Feb
Super 8 by Wyndham El Cajon/San Diego

Best Western Plus La Mesa San Diego

2.5 star property
8.2 out of 10, Very good, (1002)
"Friendly staff. Clean, comfortable room. Great breakfast. It is next to the freeway so noisy but not so noticeable in the room. "
The price is AU$215
includes taxes & fees
23 Feb - 24 Feb
Best Western Plus La Mesa San Diego

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.6 out of 10, Exceptional, (221)
"Excellent property, and good product for the price. Unexpected features like a bar and happy hour, etc. were great! Only minor issue is that hot water takes a great deal of time to get to the shower."
The price is AU$291
includes taxes & fees
21 Feb - 22 Feb
SpringHill Suites by Marriott Chula Vista Eastlake

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1130)
"great"
The price is AU$288
includes taxes & fees
16 Feb - 17 Feb
Ayres Hotel San Diego South - Chula Vista

Heritage Inn La Mesa

2.0 star property
6.2 out of 10, (1006)
"Great place to stay"
The price is AU$116
includes taxes & fees
16 Feb - 17 Feb
Heritage Inn La Mesa

Lamplighter Inn & Suites at SDSU

2.5 star property
9.0 out of 10, Wonderful, (1018)
"It was cozy and clean! Room was spacious and welcoming. Parking AND breakfast are included. My family and I are planning to stay here again when we go back to SD. Thank you staff for your attentiveness and excellent service! We appreciate it and we’ll be back! "
The price is AU$230
includes taxes & fees
11 Feb - 12 Feb
Lamplighter Inn & Suites at SDSU

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.6 out of 10, Good, (1318)
"Close to the area we need to be"
The price is AU$192
includes taxes & fees
19 Feb - 20 Feb
Best Western Chula Vista/Otay Valley Hotel

La Quinta Inn by Wyndham San Diego Chula Vista

2.5 star property
8.6 out of 10, Excellent, (1110)
"Staff is always wonderful, friendly and always able to help. Plenty parking spaces for the cars and restaurant is next to the hotel as well shopping mall. "
The price is AU$163
includes taxes & fees
2 Mar - 3 Mar
La Quinta Inn by Wyndham San Diego Chula Vista

Studio 6 Suites San Ysidro, CA -San Diego South Bay

2.5 star property
7.8 out of 10, Good, (863)
"The outside of the property smelled like sewage and the inside of the room could have been cleaner. The staff was very nice. "
The price is AU$125
includes taxes & fees
16 Feb - 17 Feb
Studio 6 Suites San Ysidro, CA -San Diego South Bay

Valli Hi Motel

2.5 star property
8.2 out of 10, Very good, (1002)
"Great "
The price is AU$146
includes taxes & fees
18 Feb - 19 Feb
Valli Hi Motel

Best Western Americana Inn

2.5 star property
8.8 out of 10, Excellent, (1072)
"Easy check in & room was clean & cozy! Great breakfast too!"
The price is AU$166
includes taxes & fees
19 Feb - 20 Feb
Best Western Americana Inn

Chula Vista Inn

2.5 star property
6.2 out of 10, (1004)
"The elevator was not working. All else was good."
The price is AU$142
includes taxes & fees
10 Feb - 11 Feb
Chula Vista Inn

Quality Inn

2.5 star property
7.6 out of 10, Good, (829)
"good area "
The price is AU$132
includes taxes & fees
19 Feb - 20 Feb
Quality Inn

Days Inn by Wyndham Chula Vista/San Diego

2.5 star property
6.2 out of 10, (812)
"there were noisy people in the next door rooms all over the night"
The price is AU$148
includes taxes & fees
10 Feb - 11 Feb
Days Inn by Wyndham Chula Vista/San Diego

Hotel Palmeras Chula Vista

2.0 star property
7.0 out of 10, Good, (1701)
"Better then expected, will be going back again. The price is low but the interior is clean and newer. Don't skip this property."
The price is AU$140
includes taxes & fees
10 Feb - 11 Feb
Hotel Palmeras Chula Vista

Hercor Hotel - Urban Boutique

3.0 star property
8.6 out of 10, Excellent, (1095)
"I loved how closed it was to the beach and how quiet it was, plus there was a taco place a cross the street ;)"
The price is AU$155
includes taxes & fees
20 Feb - 21 Feb
Hercor Hotel - Urban Boutique

Howard Johnson by Wyndham National City/San Diego South

2.0 star property
7.2 out of 10, Good, (1002)
"I didn't rent a car for my trip and was trying to go on a budget for transportation, so it worked out that this hotel is at less than 10 minutes walk from the trolley station. It's a good affordable option in a nice location that is close to both downtown and the country border."
The price is AU$131
includes taxes & fees
11 Feb - 12 Feb
Howard Johnson by Wyndham National City/San Diego South

SureStay Hotel by Best Western Chula Vista San Diego Bay

3.0 star property
7.6 out of 10, Good, (1338)
"Safe and clean "
The price is AU$134
includes taxes & fees
27 Feb - 28 Feb
SureStay Hotel by Best Western Chula Vista San Diego Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in Otay Mesa West
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

What is Otay Mesa West like?

Otay Mesa West is a neighbourhood that travellers like for its cathedral.

What's the best accommodation in Otay Mesa West?

For your stay in Otay Mesa West, Lovely 1 bd 1 bth apartment fully furnished is one of the top choices based on our traveller data. Another good option for your stay in the area is 3 Bed 2 Bath Beautiful Home - 10 Mins from the Beach!.

How many hotels are there in the Otay Mesa West area?

When you want to find places to stay in San Diego, start by booking one of Expedia's 5 hotels and other accommodation options in Otay Mesa West.

If I need to cancel my hotel reservation in Otay Mesa West, will I receive a refund?

Yes! The majority of room reservations are refundable if you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to review top deals in Otay Mesa West.

What is there to do around this San Diego neighbourhood?

A few places to visit in the area around Otay Mesa West include San Ysidro Border Crossing, Las Americas Premium Outlets and Sesame Place San Diego. While you're out sightseeing in San Diego, make sure that you visit other sights such as Tijuana Customs - Garita El Chaparral or North Island Credit Union Amphitheatre.

How can I get around Otay Mesa West and the greater San Diego area?

Ready to get out and explore the city? Iris Avenue Trolley Station is the closest metro station.