Search South San Diego Guest Houses

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
22 Aug - 24 Aug
In two weeks
29 Aug - 31 Aug
In one month
12 Sept - 14 Sept
In two months
10 Oct - 12 Oct

Featured Guest Houses in South San Diego

El Primero Hotel
Miscellaneous

El Primero Hotel

2.5 star property
9.2 out of 10, Wonderful, (1000)
"Favorite Hotel in Chula Vista"
The price is AU$181
includes taxes & fees
14 Sept - 15 Sept
El Primero Hotel
Vineyard Hacienda
BBQ/picnic area

Vineyard Hacienda

3.5 star property
9.2 out of 10, Wonderful, (520)
"Beautiful place, kind staff. We are glad we found this place!"
The price is AU$287
includes taxes & fees
17 Aug - 18 Aug
Vineyard Hacienda
Outsite San Diego - Golden Hill
Standard Double Room, 1 Double Bed

Outsite San Diego - Golden Hill

2.0 star property
9.0 out of 10, Wonderful, (17)
"I liked that all check-in details are handled online and it felt like we had the entire building all to ourselves!"
Outsite San Diego - Golden Hill
Ocean Beach Casita with hot tub, Ocean views & Garage!
Beach nearby, sun-loungers, beach towels

Ocean Beach Casita with hot tub, Ocean views & Garage!

9.8 out of 10, Exceptional, (136)
"Good place nice location. "
Ocean Beach Casita with hot tub, Ocean views & Garage!
Escape Under the Palms at Casita Las Palmas Studio Retreat
Outdoor pool

Escape Under the Palms at Casita Las Palmas Studio Retreat

10.0 out of 10, Exceptional, (66)
"The owner is so amazing and kind they will make tour stay memmorable!"
Escape Under the Palms at Casita Las Palmas Studio Retreat
New cozy studio, 2 queen beds, kitchen, walk to water!
Property grounds

New cozy studio, 2 queen beds, kitchen, walk to water!

10.0 out of 10, Exceptional, (41)
"very nice place bedding was amazing lovely decor the restaurant recommendations were spot on "
The price is AU$463
includes taxes & fees
10 Sept - 11 Sept
New cozy studio, 2 queen beds, kitchen, walk to water!
Brand new house - cleaning and sanitizing
Fridge, microwave, oven, stovetop

Brand new house - cleaning and sanitizing

10.0 out of 10, Exceptional, (104)
"The location was great and the apartment was clean, comfortable and quiet. We found it was centrally located to everything that we wanted to do and the check-in and checkout process was smooth and easy; we would definitely stay again."
Brand new house - cleaning and sanitizing
Cozy 1-bed, 1-bath, kitchenette Guest House in San Diego.
Fridge, microwave, oven, stovetop

Cozy 1-bed, 1-bath, kitchenette Guest House in San Diego.

10.0 out of 10, Exceptional, (38)
"The guest house was cozy for a family of 3. Location is a little off the beaten path if you’re looking for a place away from touristy areas. Communication was clear and timely for booking and checking in. "
The price is AU$296
includes taxes & fees
9 Sept - 10 Sept
Cozy 1-bed, 1-bath, kitchenette Guest House in San Diego.
Newly Built Guest Home
Fridge, microwave, oven, stovetop

Newly Built Guest Home

10.0 out of 10, Exceptional, (32)
"Spotless, nice location, and great host."
Newly Built Guest Home
Centrally Located, Private Bungalow with AC and parking space
Outdoor dining

Centrally Located, Private Bungalow with AC and parking space

10.0 out of 10, Exceptional, (180)
"This place is absolutely amazing we came out for a weekend getaway and couldn’t have had a better place to stay Catherine is amazing as well and very helpful with anything needed "
Centrally Located, Private Bungalow with AC and parking space
CozyCondo/GrillNights&MorningSun/2BRStay
Interior

CozyCondo/GrillNights&MorningSun/2BRStay

10.0 out of 10, Exceptional, (3)
"We had a great weekend here! The location is perfect and the host was very friendly and communicative. We thoroughly enjoyed our time here with our family."
The price is AU$384
includes taxes & fees
17 Aug - 18 Aug
CozyCondo/GrillNights&MorningSun/2BRStay
Beach Vibes
Property grounds

Beach Vibes

10.0 out of 10, Exceptional, (14)
"Debra was an excellent host and the property was great. We had a lovely view of the city and it was spectacular at night! Would definately stay here again."
Beach Vibes
Crown Point On The Water: Mission Bay
Sun-loungers, beach towels

Crown Point On The Water: Mission Bay

9.8 out of 10, Exceptional, (11)
"Had a wonderful time, the property and owner were easy to work with"
Crown Point On The Water: Mission Bay
Brand New, Ocean/City Views, 2 Decks, AC, Parking!
Fridge, microwave, oven, stovetop

Brand New, Ocean/City Views, 2 Decks, AC, Parking!

Brand New, Ocean/City Views, 2 Decks, AC, Parking!
Ocean/Sunset Views, Modern, Sunset Cliffs/Point Loma near OB, PLNU, Thurs Club
Property grounds

Ocean/Sunset Views, Modern, Sunset Cliffs/Point Loma near OB, PLNU, Thurs Club

10.0 out of 10, Exceptional, (57)
"My mom and I came out for the weekend and LOVED it. John is incredibly friendly and has a gorgeous property, it is even better than the photos. Being able to listen to the ocean right from the patio was lovely. Thank you for the wonderful experience and hospitality! We’ll be back. "
Ocean/Sunset Views, Modern, Sunset Cliffs/Point Loma near OB, PLNU, Thurs Club
Heart of SD | Zoo Nearby | Private Patio | Central
Fridge, coffee/tea maker, cookware/dishes/utensils

Heart of SD | Zoo Nearby | Private Patio | Central

7.4 out of 10, Good, (3)
"Such a great spot for a little getaway! A Cozy room with everything you need to enjoy your vacation stressfree. I would definitely stay here again in the future!"
The price is AU$302
includes taxes & fees
17 Aug - 18 Aug
Heart of SD | Zoo Nearby | Private Patio | Central
Entire 3 Bedrooms Guest House Close Beach Downtown
Exterior

Entire 3 Bedrooms Guest House Close Beach Downtown

2.5 star property
6.0 out of 10, (2)
"The owners are very nice and helpful. The property feels a bit sterile and there’s security lights and video cameras outside all up the walkway and at the entrance. The bedding was very heavy sheets for the temperature, pillows were flat. It was an ok place to spend the night but I wouldn’t want to stay more than that. "
Entire 3 Bedrooms Guest House Close Beach Downtown
Perfect guesthouse near Downtown San Diego
Fridge, microwave, oven, stovetop

Perfect guesthouse near Downtown San Diego

2.0 star property
9.0 out of 10, Wonderful, (4)
"I had a great time here! Close to the downtown area, easy parking, very cozy."
Perfect guesthouse near Downtown San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top South San Diego Hotel Reviews

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

10/10 Excellent
"Promise this a treat for anyone…..The rooms were clean and the staycation was welcoming."
Evanury 1-night trip
Posted 19 hours ago
Manchester Grand Hyatt San Diego