
Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to Santiago Intl. Airport (SCL)
- Avianca
Avianca
- Copa
Copa
- LATAM Airlines Group
LATAM Airlines Group
- Plan, book, fly with confidence
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Cheap Flights from Medellín (MDE) to Santiago (SCL)
Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.










Origin airport | José María Córdova Intl. |
Destination airport | Arturo Merino Benitez |
Airlines serving | Copa, LATAM Airlines Group, avianca |
Return price | AU$674 |
Distance | 4400 km |
Average flight time | 4 hours 55 mins |
Your quick guide to flights from Medellín to Santiago
Pick up great flights from Medellín to Santiago
With Expedia, you have your pick of flights a day with 20 airlines covering flights from Medellín to Santiago. Whether you’re on a business trip, a family holiday or a luxury break, just enter your travel dates, hit search then check out your choice of flights. Select from return, one way or multi-city flights, and use the advance search tool if you want a direct or refundable flight. You can narrow your search to show you just your preferred cabin class and airline, too. It’s all easy. You can book direct flights from Medellín to Santiago that take around hours.
Find cheap flights from Medellín to Santiago
From the great flight deals with prices currently ranging from AU$675 to AU$903, you can choose to see the cheapest flights first. Generally, you can book the cheapest flights from Medellín to Santiago around 4 to 6 weeks in advance. If your travel dates are flexible, try to avoid weekends and peak seasons – when you are more likely to grab the lowest prices. Even last minute, there are some impressive deals. The cheapest time to fly to Santiago is normally in July.
Reasons to book your flight from Medellín to Santiago with Expedia
Expedia makes it easy to find, book, and travel, with everything you need all in one place. When you enter your travel details, find fantastic deals just for you on flight tickets from Medellín to Santiago across all the main airline carriers, so you can save time, dollars, and hassle finding the perfect flight. If you think your plans could change, choose refundable flights so any changes won’t cost you more. Book your flight to Santiago right now and, if you join Expedia Rewards, you earn points this time and every time you travel with Expedia.
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Top Routes from Medellín
- Medellín to Barcelona (MDE - BCN)
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- Medellín to San Andrés (MDE - ADZ)
- Medellín to Brisbane (MDE - BNE)
- Medellín to Santa Marta (MDE - SMR)
- Medellín to Bogotá (MDE - BOG)
Top Routes to Santiago
- Newark Liberty Intl. Airport to Santiago (EWR - SCL)
- Auckland to Santiago (AKL - SCL)
- Mendoza to Santiago (MDZ - SCL)
- Cali to Santiago (CLO - SCL)
- Adelaide to Santiago (ADL - SCL)
- Cairns to Santiago (CNS - SCL)
- Cusco to Santiago (CUZ - SCL)
- Buenos Aires to Santiago (AEP - SCL)
- Gold Coast to Santiago (OOL - SCL)
- Canberra to Santiago (CBR - SCL)
- Melbourne to Santiago (MEL - SCL)
- London to Santiago (LHR - SCL)
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