Photo by Mona Zambrano

Spa Hotels & Resorts in San Ysidro from AU$122

  • Plan, book, stay with confidence
    • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Best San Ysidro Spa Hotels

Valli Hi Motel
Desk, blackout curtains, soundproofing, free WiFi

Valli Hi Motel

2.5 star property
8.2 out of 10, Very good, (954)
" Nice "
The price is AU$139
includes taxes & fees
4 Dec - 5 Dec
Valli Hi Motel
Motel 6 San Ysidro, CA - San Diego - Border
Lobby

Motel 6 San Ysidro, CA - San Diego - Border

2.0 star property
7.0 out of 10, Good, (1203)
"It’s peaceful and a friendly neighborhood "
The price is AU$129
includes taxes & fees
3 Dec - 4 Dec
Motel 6 San Ysidro, CA - San Diego - Border
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Boating

Studio 6 Suites San Ysidro, CA -San Diego South Bay

2.5 star property
7.6 out of 10, Good, (722)
"Orlando good people good service good customer service"
The price is AU$122
includes taxes & fees
15 Dec - 16 Dec
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Best Western Americana Inn
Pillow-top beds, in-room safe, desk, laptop workspace

Best Western Americana Inn

2.5 star property
8.8 out of 10, Excellent, (1073)
"Front desk clerk very friendly. Quick check in. "
The price is AU$182
includes taxes & fees
3 Dec - 4 Dec
Best Western Americana Inn
Hotel Baja San Diego - A Boutique Hotel
Exterior

Hotel Baja San Diego - A Boutique Hotel

2.5 star property
7.4 out of 10, Good, (1020)
"The hotel and staff are all excellent, my stay was cut short due to local events causing almost all the hotels in the area to be filled so I couldn't extend an this was a huge disappointment, however the staff was very curious and even helped me look for hotels and gave me advice to better prepare for my next stay, all in all I would say this hotel was a 4.5/5"
Hotel Baja San Diego - A Boutique Hotel
Cozy and quiet 6-bedroom retreat close to outlet mall shopping and more!
Outdoor dining

Cozy and quiet 6-bedroom retreat close to outlet mall shopping and more!

10.0 out of 10, Exceptional, (2)
"Amidst a quaint neighborhood, Carl and Dora’s property provided respite for our group. Conveniently located near common stores, like Costco, and Target, it was also close to the outlets for shopping, the Mexican border for out of country tourism, and is a quick 15-20 minute drive to San Diego for enjoyment of districts such as Old Town, Little Italy and the Gaslamp/Downtown area. Communication was very kind and prompt. Truly great hosts. 11/10 would recommend."
Cozy and quiet 6-bedroom retreat close to outlet mall shopping and more!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in San Ysidro
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until 4 Dec (property time) with our Black Friday deals. Stay by 15 Dec 2025.
Unlock Black Friday deals

Frequently asked questions

Looking for a spa hotel in San Ysidro?
Treat yourself to some time in a luxurious spa hotel and you won’t regret it. Travellers recommend the popular shops and gourmet restaurants in San Ysidro. Enjoy the live music and beaches during your holiday. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in San Ysidro?
Best Western Americana Inn is a top spa hotel featuring a rooftop terrace and an outdoor pool.
How many spa hotels will I find in San Ysidro?
Among Expedia’s 11 accommodation options in San Ysidro, there are 2 spa hotels.
What's there to see and do in San Ysidro?
Take in some sights and attractions while you’re in San Ysidro by visiting San Ysidro Border Crossing, Las Americas Premium Outlets and San Diego Zoo. If you have a little extra time during your trip, you might want to check out Mission Bay and Petco Park.
What is a San Ysidro spa hotel?
Spa hotels in San Ysidro provide lodging and have an on-site spa offering services such as massages and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on holiday.